Pueraria,the other popular name is Kudzu.It is a fast-growing vine native to the subtropical regions of China and Japan. The stems that can grow to 20 m (60 ft) in length with extensive roots, the leaves contain 3 broad oval leaflets with purple flowers and curling tendril spikes.
And the plant is a vine. Under the right growing conditions, it spreads easily, covering virtually everything that doesn’t move out of its path. Kudzu was introduced in North America in 1876 in the southeastern U.S. to prevent soil erosion. But kudzu spread quickly and overtook farms and buildings, leading some to call to kudzu "the vine that ate the South.”
Kudzu’s root, flower, and leaf are used to make medicine. It has been used in Chinese medicine since at least 200 BC. As early as 600 AD, it was used to treatalcoholism.
Figure 1 Parts of Pueraria
Pueraria is the root of leguminous plants Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth. perennial lianas herb, Flower period is from April to August and the fruit is from August to October. It was born in mountain forests or roadside. it is distributed in Henan, hunan and zhejiang province,has grown in most areas of China.
Figure 2 Pueraria planting farm
Introduction of Pueraria/Kudzu Extract
Pueraria/Kudzu Extract is typically derived from the root . As an herbal supplement, the extract has long been prized for its reputation of having Medicinal value, clinical application,and Health diet. It is a unique source of the isoflavones, puerarin,also contains a number of flavonoids ingredients, including daidzein,daidzin,Genistein, puerarin-7-xyloside and so on.
Figure 3 Pueraria 99.5% COA
Our company select high-quality raw materials, natural pollution-free.The content of active ingredient could reach puerarin 99.5% HPLC,isoflavones 40% HPLC.Puerarin has enhances the immunity, enhance myocardial contractility, protect myocardial cells, reduce blood pressure, inhibit platelet aggregation function.Flavonoids can improve blood circulation, lower cholesterol, improve the symptoms of cardiovascular disease,also can promote wound healing and pain relief, for all kinds of allergies. In traditional Chinese medicine,it’s used to treat tinnitus, vertigo, and Wei syndrome. Research in mice models suggests that it is beneficial in women for control of some post-menopausal symptoms, such as hypertension and diabetes type II.
Main Specification of Pueraria/Kudzu Extract
1. Puerarin HPLC 80% 99.5%.
Puerarin is a flavonoid derivative from the traditional oriental medicine, Ge-gen. Purarin has potential antioxidant activity and impairs CYP catalyzed drug metabolism. A metabolite, calycosin, shows cytotoxic activity. Puerarin is an inhibitor of SR-2C (5-HT2C receptor) .
A crude extract of Radix puerariae suppresses the free-choice ethanol intake of ethanol-preferring golden Syrian hamsters due to two of its isoflavones, daidzin and daidzein. This root extract was found to contain 15% ~ 30% puerarin as the main constituent and smaller amounts of the related isoflavonoids 3'-hydroxypuerarin, 3'-methoxypuerarin, 6''-xylosylpuerarin, daidzin, genistin, daidzein and genistein.
Figure 5 HPLC of Pueraria Root Extract
3. Pueraria Flower Extract 5:1
extracts from the dried flower of Pueraria thomsonii on blood ethanol and acetaldehyde levels in humans consuming alcoholic beverages. The extracts of Pueraria thomsonii had no influence on blood ethanol and acetaldehyde concentration in humans. However, the extracts increased the elimination rate constant of blood acetaldehyde, although they had no effect on the elimination of blood ethanol in humans. These results suggest that Pueraria thomsonii promotes the elimination of blood acetaldehyde in humans. The present study clinically suggests that a modest stimulatory effect of Pueraria thomsonii on the elimination of blood acetaldehyde may passively mitigate acetaldehyde toxicity, such as flushing, palpitation, headache, etc., associated with excessive alcohol intake.
Figure 6 Pueraria Flower Extract
There is information that suggests kudzu contains ingredients that counteract alcohol. It might also have effects like estrogen. Chemicals in kudzu might also increase blood circulation in the heart and brain.
Some people use kudzu for menopause symptoms, muscle pain, measles, dysentery, stomach pain (gastritis), fever, diarrhea, thirst, neck stiffness, and to promote sweating. Other oral uses include treatment of polio myelitis, encephalitis, migraine, deafness, diabetes, and traumatic injuries.
Health providers in China sometimes give puerarin, a chemical in kudzu, intravenously (by IV) to treat stroke due to a blood clot.
Today, kudzu is also used to treat alcoholism and to reduce symptoms of alcohol hangover, including headache, upset stomach, dizziness, and vomiting. Kudzu is also used for heart and circulatory problems, including high blood pressure, irregular heartbeat, and chest pain; for upper respiratory problems including sinus infections, the common cold, hay fever, flu, and swine flu; and for skin problems, including allergic skin rash, itchiness, and psoriasis.
1.As the crud drug for cardiovascular drugs, it is widely used in biopharmaceuticals;
2.With a unique effect for lipid-lowering, it is widely used to be added into foods and health products;
3.With a unique effect of phytoestrogen ,it is widely used in cosmetics field to defer senility
How to use (dosage) ?
The recommended dosage for Kudzu extract UV40% is 50mg to 100mg per day, depending on the individual’s needs. Some Chinese herbalists recommend up to 100mg every day.
1.The prevention of hepatitis, improve liver detoxification function, repair the liver damage of cell populations;
2. High blood pressure, high cholesterol, high blood sugar and cardio-cerebrovascular diseases such as migraine patients;
3. Menopausal women, easily irritated people, commonly used alcohol, tobacco.
It is better not to eat together with wine,since it maybe combine into a toxic substance.
Figure 7 Dosage
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